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The mRNA vaccines developed by Pfizer and Moderna during the COVID-19 pandemic worked on entirely different principles from traditional vaccines, dramatically cutting the development timeline.

How do mRNA vaccines train the body's immune system?

By injecting the genetic blueprint (mRNA) for a viral protein, prompting the body's own cells to produce the antigen directly
The injected mRNA never enters the cell nucleus — ribosomes in the cytoplasm use it to produce spike proteins, after which the mRNA naturally breaks down within days, leaving DNA completely unaltered.
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